LbCas12a

Product Introduction

LbCas12a can recognize the PAM sequence TTTN site under RNA mediation; after cutting the target, it produces "collateral cleavage" activity, cutting any sequence single-stranded DNA. By designing probes with fluorescent or other small molecule markers at both ends, signal amplification for DNA detection can be achieved, thus enabling detection of the target. This system has high sensitivity and strong specificity.

Product Feature

- Compared to Cas9, Cas12a protein is smaller and easier to deliver to cells;

- Wide reaction temperature range of 20-48°C;

- After cutting the target, it produces "collateral cleavage" activity, cutting any sequence single-stranded DNA.

Product Application

- Gene editing;

- Combined with isothermal amplification technology, rapid detection of nucleic acids can be achieved.

Product Data

SDS-PAGE electrophoresis

Figure 1. CSB-DEM028 LbCas12a SDS-PAGE Electrophoresis Image.